Best Flea Drops For Dogs

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In a rush and just want my recommendation?  I think the K9 Advantix II Flea and Tick Prevention for Large Dogs is a great choice.

Fleas are a prevalent issue for many dogs and their owners. When your pet gets fleas or any other pest living in their coat, you need to do all you can to get rid of it. But what is even better is to prevent fleas from arriving in the first place. In this article, we will show you a few of the best flea drops for dogs that will help you do that. 

In this article, I’m reviewing the following flea drops for dogs.

5 Best Flea Drops For Dogs Reviewed

K9 Advantix II Flea and Tick Prevention for Large Dogs

Nearly all flea drops will make the statement that they are long-lasting. But not every product works as quickly as it might claim. However, when it comes to K9 Advantix II Flea and Tick Prevention for Large Dogs, fast action is the name of the game. 

This formula starts working in less than half a day. But that is not the only benefit of using the K9 Advantix II Flea and Tick Prevention for Large Dogs. This formula not only gets to work quickly but also lasts for a while. When using this flea drop option, your dog will remain flea-free for 30 days on a single treatment. 


  • Begins working within 12 hours
  • Lasts for 30 days
  • Works on multiple pests


  • Some dogs have a reaction
  • Causes skin irritation in some cases

Frontline Plus Flea and Tick Treatment for Dogs

I’ve owned several dogs in my lifetime. So, I know that it can be hard to find products that work well for dogs of all sizes. If you are ever looking for a flea treatment for larger dogs, Frontline Plus Flea and Tick Treatment for Dogs is one of your best options. 

Like other flea protection products, this formula kills fleas during all parts of the flea’s life cycle. But despite what the maker says, this product is not the best for getting rid of ticks. Still, for someone with a dog that weighs more than 45 pounds, Frontline Plus Flea and Tick Treatment for Dogs is a great option. 


  • Great for medium and large dog breeds
  • Waterproof
  • Kills fleas at all stages
  • Intuitive applicator


  • Not the most fast-acting
  • Not the best for ticks

Hartz UltraGuard Dual Action Topical Flea & Tick Treatment

Hartz UltraGuard Dual Action Topical Flea & Tick Treatment is a product that claims to eliminate fleas and ticks from your dog’s coat. This flea drop comes in a pack of three easy monthly applications.

Compared to other products on this list, the Hartz UltraGuard Dual Action Topical Flea & Tick Treatment is not the most long-lasting and is not suitable for large dog breeds. Instead, it is ideal for dogs that weigh between 15 and 30 pounds. 


  • Single treatments each month
  • Works on multiple pests
  • Fast-acting


  • Not the most long-lasting
  • Does not work for larger dogs

SENTRY Fiproguard for Dogs

SENTRY Fiproguard for Dogs is an excellent option for those with smaller dogs and pregnant or breeding dogs. This formula is ideal for dogs that weigh between 5 and 22 pounds but is suitable for all ages. 

Along with fighting fleas, this flea drop product is excellent for lice and mites that cause mange as well. However, SENTRY Fiproguard for Dogs is not perfect for every dog as it can cause some side effects like allergies and diarrhea. 


  • Useful for puppies and kittens
  • Can be used for pregnant dogs
  • Waterproof
  • Works on multiple pests


  • Not good for dogs with allergies
  • Can cause diarrhea

Solimo Flea and Tick Topical Treatment

The best flea drops are those that fight fleas during all stages of the flea’s life cycle. That is what you get when you choose the Solimo Flea and Tick Topical Treatment.

This product kills fleas while they are eggs, larvae, and fully grown. It also lasts for more than 30 days and can kill deer ticks too. 

The Solimo Flea and Tick Topical Treatment do not work on all pests, especially those that come from Texas and Florida. But otherwise, this is a great flea treatment option. 


  • Kills fleas at all stages
  • Long-lasting formula
  • Very affordable


  • Does not work on pest from all areas of the country
  • Causes skin damage in some cases

What to Look for in Flea Drops for Dogs

To equip you with the knowledge you need to evaluate one of these products, we have created a quick buyer’s guide. Read on in the sections below to see what you should consider when buying a flea treatment for your dog. 

Fast Action

Ideally, the flea treatment you choose for your dog should be fast-acting. A fast-acting flea treatment begins working right away rather than having a lag time. The sooner that the treatment you choose begins working, the sooner your dog can relieve their flea issue. 

With so many flea drops for sale, you find that some work more quickly than others. The challenge is that many products will claim that their formula works quickly. But that is not always the case. 

Before you settle on a flea drop for your dog, you need to know the reality behind the brand’s fast-acting claim. For the products on our list, we will point out which ones have the fastest action. 

Length of Effectiveness

As much as you want your flea drops to work quickly, you also want them to be long-lasting. Fortunately, a durable formula is something many companies strive for in these products.

The longer that your flea drops last, the less often you will need to continue applying the treatment to your dog. A long-lasting flea drop makes for an easy, flea-free lifestyle for you and your pet. Often, a few applications of these products can last for a month or more. A good flea-collar can be an alternative if you need continued protection for your hound.

Easy Application

Many pet owners know that their dogs will not sit still for any type of medical treatment. Others don’t want to get involved with any complicated pet care routines. 

To meet those two desires, you need to choose a flea drop product that comes with easy application. Typically, these products require you to apply them somewhere on your dog’s back. Often, direct contact between the formula and your pet’s skin will work best. 

Waterproof Solution

It is also important that the flea drop you choose has a waterproof solution. That waterproofing allows the formula to take effect in any setting. 

A playful dog is often happy to run in the rain or splash in puddles. If your flea drop treatments are not waterproof, they may dissolve as your pup plays. That is why it is vital that you choose a waterproof flea drop for your dog. 

Defense Against Other Pests

One of the most convenient aspects of the best flea drops for dogs is that many of them protect against other pests as well. It is common to find many of these products that work well for eliminating fleas and these other nuisances:

  • Ticks 
  • Mosquitos
  • Mites
  • Lice

Each of those unwanted visitors can harm your dog’s health. A multi-purpose flea drop will help make sure that such problems don’t arise. 

Suitable Pet Age

When you shop for a flea drop solution for your dog, you’ll notice that some options are better for specific age ranges. Make sure that you select a product that is suitable for your pet’s current age. Additionally, some formulas are suitable for pregnant dogs while others are not. 

Pet Weight Range

Just as there is an age range for certain flea drops, there is often a weight range as well. Some products will be ideal for smaller dogs, while others are better for large dogs. Knowing the weight of your dog in advance will help you pick the best formula for them. 

Dosage and Number of Applications

Any treatment you use is only as effective as your skill in application. Each of the products you browse will come with a unique set of instructions directing you towards proper use. 

Each flea drop formula will tell you how much to put on your dog as well as where and how to put it on. You should also know the recommended frequency of application so that you can enjoy the best results of your flea drops for your dog. 


While it is difficult to pick one winner, our selection for the top honor goes to K9 Advantix II Flea and Tick Prevention for Large Dogs. This product delivers on everything you would expect from the best flea drops. It works quickly, lasts a while, and kills multiple kinds of pests. 

Along with those advantages, you need to make sure that you choose a flea drop that is easy to apply and is waterproof. That way, you won’t have any issue getting flea treatment on your dog’s skin and keeping it there.

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